10-1555
ML241
Größe
£187.00
- SKU:
- 10-1555
- Zusätzliche Namen:
- CID49830260
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 372.46
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1346528-06-0
- Immunogen:
- ATPase|ER/Golgi|UPR (Unfolded protein response)
- Weitere Details:
- Potent and selective p97 AAA ATPase inhibitor, IC50=100 nM. Inhibits degradation of a p97-dependent but not p97-independent proteasome substrate in a dual-reporter cell line1. It impairs the endoplasmic reticulum-associated degradation (ERAD) pathway.1 ML241 and related inhibitors (DBeQ for example) have differential responses to p97 mutants as well as the presence of cofactors suggesting the possibility of context-dependent p97 inhibitors.2,3
- Versandbedingungen:
- Ambient