GAC Inhibitor 968

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£149.00

SKU:: 10-1538
Physischer Zustand:: Solid
Molekulargewicht:: 475.42
Reinheit:: 98%
Lagerbedingungen:: RT
Hersteller:: Focus Biomolecules
CAS Number:: 311795-38-7
Immunogen:: Energy production|Glutaminase
Weitere Details:: Allosteric inhibitor of glutaminase C (GAC).1 Inhibition of GAC blocks oncogenic transformation induced by Rho GTPases in fibroblasts and B lymphoma cells with no effect on normal cells.2 Inhibits liver-type glutaminase GLS2 and suppresses breast tumor growth in vivo.3,4 Reverses acquired erlotinib resistance in non-small cell lung cancer.5