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10-1525

MitoBloCK-12

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£139.00

SKU:
10-1525
Zusätzliche Namen:
DECA|Dequalinium chloride|MB12
Physischer Zustand:
Solid
Molekulargewicht:
527.58
Reinheit:
>98%
Lagerbedingungen:
RT
Hersteller:
Focus Biomolecules
CAS Number:
522-51-0
Weitere Details:
Attenuates mitochondrial protein import (4-10 uM). Discovered in a screen of FDA-approved drugs. Blocks translocation of a mutant form of alanine: glyoxylate aminotransferase (AGT) to the mitochondria and restores AGT trafficking to peroxisomes.1 Also reduces oxalate accumulation and thus has potential to treat patients with primary hyperoxaluria 1 who possess mutations in AGT.1 Also displays antimicrobial activity2, inhibits apamin-sensitive K+ channels3 and induces apoptosis by inhibiting XIAP4.
Versandbedingungen:
Ambient