Fascaplysin

Größe

£139.00

SKU:: 10-1517
Physischer Zustand:: Solid
Molekulargewicht:: 306.75
Reinheit:: 98%
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 114719-57-2
Immunogen:: Kinase
Weitere Details:: A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 uM) and is less selective for Cdk6/D1 (IC50 = 3.4 uM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.