10-1510
STF-083010
Größe
£149.00
- SKU:
- 10-1510
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 317.39
- Reinheit:
- 98%
- Lagerbedingungen:
- RT
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 307543-71-1
- Immunogen:
- RNA|UPR (Unfolded Protein Response)
- Weitere Details:
- A novel small molecule inhibitor of IRE1. It inhibits IRE1 endonuclease activity but not its kinase activity after endoplasmic reticulum stress1-3. It displays significant antimyeloma activity in model human MM xenografts1. Induces apoptosis in pancreatic cancer cells and displays growth inhibition in a clonogenic growth assay in soft agar as well as in a xenograft in vivo model of pancreatic cancer4. Active in vivo.
- Versandbedingungen:
- Ambient