LY364947

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£173.00

SKU:: 10-1492
Zusätzliche Namen:: HTS-466284
Physischer Zustand:: Solid
Molekulargewicht:: 272.31
Reinheit:: 98%
Lagerbedingungen:: RT
Hersteller:: Focus Biomolecules
CAS Number:: 396129-53-6
Immunogen:: Kinase
Weitere Details:: Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-B Beta RI, TGF-B Beta RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-B Beta as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.