HTS01037

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£158.00

SKU:: 10-1453
Physischer Zustand:: Solid
Molekulargewicht:: 337.37
Reinheit:: 98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: RT
Hersteller:: Focus Biomolecules
CAS Number:: 682741-29-3
Immunogen:: FABP (Fatty acid binding protein)
Weitere Details:: Inhibits fatty acid binding proteins. Inhibits lipolysis in 3T3-L1 adipocytes and reduces LPS-stimulated inflammation in cultured macrophages. Acts as an antagonist of the protein-protein interaction between AFABP/aP2 and hormone sensitive lipase but does not activate PPARG Gamma in macrophages1. Inhibits FABP-dependent and fatty acid-stimulated leukotriene C4 biosynthesis2. Reduces intracellular free fatty acid levels, lowering macrophage inflammation and ER stress3. Reduces LPS-stimulated IL-1B Beta secretion in a mouse model4. Inhibits VLDL-induced foam cell formation5.