10-1443
680C91
Größe
£166.00
- SKU:
- 10-1443
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 238.27
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 163239-22-3
- Immunogen:
- Tryptophan
- Weitere Details:
- A potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) Ki=42 nM)1,2. Displays no activity against indoleamine 2,3-dioxygenase, MAO-A and B and does not effect serotonin uptake. Elevates CSF tryptophan by up to 260% and CSF serotonin by 170% of basal2. TDO inhibition by 680C91 in glioma cells blocked the release of kynurenine, an endogenous tumor promoting AHR ligand4.
- Versandbedingungen:
- Ambient