10-1425
Gue1654
Größe
£158.00
- SKU:
- 10-1425
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 447.59
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 397290-30-1
- Immunogen:
- GPCR
- Weitere Details:
- Gue1654 is a biased antagonist for the oxoeicosanoid receptor 1 (OXE-R, GPR170)1, the receptor for 5-Oxo-ETE, a proinflammatory eicosanoid2. It selectively inhibits GB BetaG Gamma but not GA Alphai signaling upon activation of the GA Alphai-B BetaG Gamma heterotrimer by OXE-R.1,3 Gue1654 alleviated coronary artery ligation-induced ischemic myocardial injury in a mouse model.4
- Versandbedingungen:
- Ambient