10-1421
CZC-54252
Größe
£182.00
- SKU:
- 10-1421
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 541.46
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1191911-27-9
- Immunogen:
- Kinase
- Weitere Details:
- Novel, potent and selective inhibitor of the leucine-rich repeat kinase-2 (LRRK2), IC50 = 1.28 nM. Also inhibits G2019S mutant LRRK2, IC50 = 1.85 nM1. Attenuates the neuronal damage elicited by the action of LRRK2 G2019S mutant in primary human neurons (EC50 = 1 nM)1. The G2019S mutant is a common mutation found in familial Parkinson's disease patients2. Cell permeable.
- Versandbedingungen:
- Ambient