10-1412
Importazole
Größe
£149.00
- SKU:
- 10-1412
- Zusätzliche Namen:
- IPZ
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 318.43
- Reinheit:
- 97%
- Lagerbedingungen:
- RT
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 662163-81-7
- Immunogen:
- Cytoskeleton
- Weitere Details:
- Specifically inhibits importin-B Beta-mediated nuclear import without disrupting transportin-mediated nuclear import or CRM1-mediated nuclear export1. When added to cells during mitosis it impairs the release of an importin- cargo probe and causes defects in spindle assembly. Inhibition of importin-B Beta function is most likely mediated by blocking its interaction with RanGTP. It is an important new tool to probe the function of the importin-/RanGTP pathway2-4. Cell permeable
- Versandbedingungen:
- Ambient