Epoxomicin

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£200.00

SKU:: 10-1384
Physischer Zustand:: Solid
Molekulargewicht:: 554.73
Reinheit:: 97%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 134381-21-8
ABP:: No Import Docs
Immunogen:: Proteasome
Weitere Details:: Epoxomicin is a potent, selective and cell permeable irreversible inhibitor of the 20S proteasome.1 It does not inhibit non-proteasomal proteases such as papain, chymotrypsin, trypsin, calpain and cathepsin B at concentrations up to 50 uM.1 Epoxomicin was isolated from Actinomycete strain Q996-17 and displayed in vivo antitumor activity against B16 melanoma cells.2 Epoxomicin caused a progressive model of Parkinson's disease in various systems.3,4,5 This model has been disputed.6,7