10-1360
FQI1
Größe
£168.00
- SKU:
- 10-1360
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 311.33
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 599151-35-6
- Immunogen:
- Transcription factor
- Weitere Details:
- Inhibitor of transcription factor LSF specifically targeting its DNA binding and corresponding transcriptional activity (IC50=2.1 M). Rapidly induces apoptosis in an aggressive hepatocellular carcinoma (HCC) cell line and dramatically inhibits tumor growth in a mouse xenograft model with no general tissue cytotoxicity.1,2 In human HCC cells, FQI1 induced mitotic arrest with an accompanying increase in cyclin B1.3 Blocks LSF-stimulated activation of DNA methyltransferase 1.4 Cell permeable.
- Versandbedingungen:
- Ambient