10-1353
Wiskostatin
Größe
£153.00
- SKU:
- 10-1353
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 426.15
- Reinheit:
- 98%
- Lagerbedingungen:
- RT
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 253449-04-6
- Immunogen:
- Cytoskeleton
- Weitere Details:
- A selective, reversible inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity1. Binds to the regulatory domain of N-WASP and inhibits activation of Arp2/3 complex by forcing N-WASP into an inactive conformation2. Inhibits PIP2-induced actin polymerization (EC50=4 uM). Perturbs agrin-elicited acetylcholine receptor clustering3. Inhibits the formation of dendritic spines and synapses in hippocampal neurons4.
- Versandbedingungen:
- Ambient