10-1352
NSC663284
Größe
£187.00
- SKU:
- 10-1352
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 321.77
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 383907-43-5
- Immunogen:
- Phosphatase
- Weitere Details:
- Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B1. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation2. Inhibits the growth of a variety of human tumor cell lines3. Acts via irreversible oxidation of the catalytic cysteine of CDC254.
- Versandbedingungen:
- Ambient