Glyburide

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£129.00

SKU:: 10-1325
Zusätzliche Namen:: Glibenclamide
Physischer Zustand:: Solid
Molekulargewicht:: 494.01
Reinheit:: 98%
Lagerbedingungen:: RT
Hersteller:: Focus Biomolecules
CAS Number:: 10238-21-8
Immunogen:: Inflammasome|Ion channel
Weitere Details:: Second generation oral hypoglycemic agent. Acts via ATP-dependent K+ channel (Kir6, KATP) block1. Inhibits Kir6 currents in the pancreas, causing an increase in intracellular Ca2+ and insulin secretion. Also inhibits recombinant CFTR Cl- channels with an IC50 of 20 uM2. Cell permeable.