10-1268
Cytarabine
Größe
£139.00
- SKU:
- 10-1268
- Zusätzliche Namen:
- Ara-C|Arabinocytidine|Cytosine B Beta-D-Arabinofuranoside|U-19920A
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 243.22
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 147-94-4
- Immunogen:
- DNA|RNA
- Weitere Details:
- A nucleoside analog that interferes with DNA synthesis and transcription, particularly in tumor cells.1,2 It Cellular enzymes convert it to its nucleotide form, Ara-CTP, which disrupts DNA and RNA synthesis when polymerases attempt to incorporate it.3,4 For the same reasons, it is also employed as an antiviral.5 It inhibits proliferation of a variety of leukemic cell lines (IC50s 16-72 nM), but is used primarily against acute myeloid leukemia (AML).6,7
- Versandbedingungen:
- Ambient