Calyculin A

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SKU:: 10-1230
Physischer Zustand:: White solid or film (Note. Vials may appear empty)
Molekulargewicht:: 1009.18
Reinheit:: >98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 101932-71-2
Immunogen:: Phosphatase
Weitere Details:: Calyculin A (101932-71-2) is a potent cell permeable inhibitor of protein phosphatase 1 (PP1) and 2A (PP2A), IC50=0.3-1 nM.1 Has no effect on PP2B, PP2C as well as acid or alkaline phosphatase at 1 mM.2 A non-phorbol tumor promoter.3 Stimulates the phosphorylation of various cellular proteins such as vimentin4 and NFkB5 and also induces membrane translocation of protein kinase C6.