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10-1211

ODQ

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£129.00

SKU:
10-1211
Physischer Zustand:
Solid
Molekulargewicht:
187.15
Reinheit:
98%
Aufreinigung:
HPLC Purified
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
41443-28-1
Immunogen:
Guanylyl cyclase
Weitere Details:
A potent and selective inhibitor of soluble guanylyl cyclase (sGC), IC50 = 20 nM).1 ODQ acts via competition with NO for the heme site of sGC where it binds irreversibly.2 ODQ does not inhibit NO-mediated macrophage toxicity, an activity that is unrelated to cGMP nor does it inhibit particulate GC.1 ODQ is an extremely useful tool to explore the involvement of the NO-cGMP pathway in cellular signaling and physiologic processes.3-5
Versandbedingungen:
Ambient