Antazoline HCl

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£143.00

SKU:: 10-1144
Physischer Zustand:: Solid
Molekulargewicht:: 301.82
Reinheit:: >98%
Lagerbedingungen:: RT
Hersteller:: Focus Biomolecules
CAS Number:: 2508-72-7
Immunogen:: GPCR|Ion channel
Weitere Details:: Antazoline (2508-72-7) displays neuroprotective effects against hypoxia-induced death in neuronal cultures, the mechanism of action being inhibition of NMDA currents (IC50=4 uM).1 It induces concentration-dependent stimulation of insulin secretion in rat pancreas which is mediated via imidazoline I1 receptors.2 It also acts as a histamine H1 receptor antagonist (Ki=38.4 nM, human recombinant H1 receptor)3 and was found to be a highly effective antiarrhythmic agent4.