Mirin

Größe

£149.00

SKU:: 10-1069
Physischer Zustand:: Solid
Molekulargewicht:: 220.25
Reinheit:: 98%
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 299953-00-7
Immunogen:: DNA
Weitere Details:: Mirin is an inhibitor of the Mre11-Rad50-Nbs1(MRN) complex (IC50 = 12 uM for inhibition of ATM activity), part of the MRN-ATM(ataxia-telangiectasia mutated) pathway, an essential pathway for sensing and signaling from DNA double-strand breaks. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.