A-803467

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£149.00

SKU:: 10-1066
Physischer Zustand:: Solid
Molekulargewicht:: 357.80
Reinheit:: 98%
Lagerbedingungen:: RT
Hersteller:: Focus Biomolecules
CAS Number:: 944261-79-4
Immunogen:: Ion channel
Weitere Details:: Potent, selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8. Nav1.8 is preferentially expressed in sensory neurons, and inhibition attenuates both inflammatory and neuropathic pain in a variety of animal models. IC50's for rat and human Nav1.8 are 140 nM and 8.0 nM respectively.