Goat anti Human Factor XII

Eine Lieferung in diese Region ist nicht möglich.

SKU:: NM-GAHU-FXII
Quelle:: Factor XII (Hageman factor) is a single chain glycoprotein (MW 80,000). It is a serine protease zymogen. FXII is converted to an active enzyme by damage to vascular endothelium. In vitro activation is caused by glass or kaolin. Surface binding promotes activation by kallikrein. FXIIa activates prekallikrein and FXI. Kallikrein activates more FXII. Fragments of FXIIa activate FVII to FVIIa, and plasminogen to plasmin. The complement system is also activated by FXIIa. A link between fibrin clot and the subendothelium is formed by FXIIa crosslinking with fibrin, alpha-2 plasmin inhibitor, fibronectin and Van Willebrand factor. Purified plasma FXII is used as immunogen. Freund's complete adjuvant is used in the first step of the immunization procedure.
Hersteller:: Exalpha / Nordic Mubio
Host:: Goat
Formulierung:: Delipidated, heat inactivated, lyophilized, stable whole serum. No preservative added. Total protein concentration in the antiserum is about 50 mg/ml, the IgG concentration about 10 mg/ml. No foreign
Klonalität:: Polyclonal
Format:: Delipidated, heat inactivated, lyophilized, stable whole serum. No preservative added. Total protein concentration in the antiserum is about 50 mg/ml, the IgG concentration about 10 mg/ml. No foreign