SOX2 Monoclonal Antibody

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£344.70

War £383.00

SKU:: ELAB6940-R
Zusätzliche Namen:: SOX2
Anwendung:: IHC-P
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles. Protect from light.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Weitere Details:: The SOX2 gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors, which plays an important role in early organ development. SOX2 can be used in the auxiliary diagnosis of germ cell tumors. 90% of embryonic cancers express SOX2, but not in seminoma, yolk sac tumor and choriocarcinoma. SOX2 has been shown to be a negative prognostic factor and associated with aggressive phenotypes in breast, head and neck, gastric, colorectal and bladder cancers. In small cell lung cancers, SOX2 was also correlated with a poor prognosis. Conversely, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and was shown to be an independent positive prognostic marker.