QuicKey Pro Rat sCD14 (Soluble Cluster of Differentiation 14) ELISA Kit

Größe

£128.70

War £143.00

SKU:: E-OSEL-R0020
Zusätzliche Namen:: CD14 Antigen, Monocyte Differentiation Antigen CD14
Anwendung:: ELISA
Physischer Zustand:: Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:: Rat
Lagerbedingungen:: 2-8[o]C
Hersteller:: Elabscience
Format:: Colorimetric method,ELISA,Sandwich
Uniprot:: Q63691
Synonyme:: CD14 antigen;monocyte differentiation antigen CD14;myeloid cell-specific leucine-rich glycoprotein
Weitere Details:: sCD14 is an important inflammatory marker that plays a key role in the body's immune-inflammatory response. It is a soluble molecule generated by the hydrolysis of CD14 molecules on the surface of macrophages. CD14 mainly consists of two forms: a glycoprotein expressed on the cell membrane surface (mCD14) and soluble CD14 (sCD14) formed after secretion or shedding into the bloodstream. The main function of sCD14 is to act as a receptor for endotoxin lipopolysaccharide (LPS). When mononuclear macrophages receive inflammatory signal stimulation from LPS, sCD14 promotes the secretion and expression of various cytokines through related signal transduction pathways.