E-OSEL-M0005
QuicKey Pro Mouse IgG(Immunoglobulin G) ELISA Kit
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£128.70
War £143.00
- SKU:
- E-OSEL-M0005
- Zusätzliche Namen:
- Ighg
- Anwendung:
- ELISA
- Physischer Zustand:
- Plasma, Serum
- Spezies-Reaktivität:
- Mouse
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P01863
- Synonyme:
- Immunoglobulin heavy chain gamma polypeptide
- Weitere Details:
- There are five classes of mammalian immunoglobulins:IgA, IgD, IgE, IgM, and IgG. IgG is the most abundant immunoglobulinand is equally distributed in blood and tissue. In mice, the IgG class isfurther divided into four subclasses: IgG1, IgG2a IgG2c (strain specific),IgG2b, and IgG3. The general immunoglobulin structure is composed offour polypeptide chains, two heavy and two light chains linkedtogether and to each other by disulfide bonds, creating a tetramericquaternary structure. The resulting tetramer creates two identicalhalves which together form a Y like structure. While the amino-terminalportions that exhibits highly variable amino-acid composition areinvolved in antigen binding, the C terminal constant parts are involvedin complement binding, placental passage and binding to cellmembrane. IgG is involved in response to a foreign antigen. Thepresence of IgG usually signifies a mature antibody response. IgG has amolecular weight of about 150 kDa, it can bind to many pathogensand also plays an important role in antibody-dependent cell-mediatedcytotoxicity. Typically, mouse serum and plasma samples containabout 7 to 10 mgml of IgG.
- Versandbedingungen:
- Blue Ice