Mini Sample Mouse CD48 (Cluster Of Differentiation 48) ELISA Kit

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£128.70

War £143.00

SKU:: E-MSEL-M0123
Zusätzliche Namen:: CD48,BLAST-1,BCM-1,SLAMF2
Anwendung:: ELISA
Physischer Zustand:: Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:: Mouse
Lagerbedingungen:: 2-8[o]C
Hersteller:: Elabscience
Format:: Colorimetric method,ELISA,Sandwich
Uniprot:: P18181
Synonyme:: AI449234;AW610730;Bcm-1;BCM1;BCM1 surface antigen;BLAS;BLAST;BLAST-1;BLAST1;CD48 antigen;HM48-1;MEM-102;MRC OX-45 surface antigen;Sgp-;Sgp-60;signaling lymphocytic activation molecule 2;SLAM family member 2;SLAMF2
Weitere Details:: Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation.Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation.Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.