Mini Sample Mouse BLC (B-Lymphocyte Chemoattractant) ELISA Kit

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£128.70

War £143.00

SKU:: E-MSEL-M0114
Zusätzliche Namen:: CXCL13,ANGIE,ANGIE2,BCA-1,BCA1,BLR1L,SCYB13
Anwendung:: ELISA
Physischer Zustand:: Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:: Mouse
Lagerbedingungen:: 2-8[o]C
Hersteller:: Elabscience
Format:: Colorimetric method,ELISA,Sandwich
Uniprot:: O55038
Synonyme:: 4631412M08Rik;ANG;Angie;ANGIE2;B lymphocyte chemoattractant;BCA-;BCA-1;BL;BLC;BLR1L;C-X-C motif chemokine 13;CXC chemokine BLC;Scyb1;Scyb13;small inducible cytokine subfamily B (Cys-X-Cys), member 13;small-inducible cytokine B13
Weitere Details:: CXCL13/BLC/BCA-1 is a constitutively expressed chemokine that plays an important role in B and T cell homing. It is expressed by salivary gland epithelium, dendritic cells, osteoclasts, and peritoneal macrophages. It can form homodimers or heterodimers with FGF basic, and it signals through CXCR3 or CXCR5. CXCL13 induces the migration of naive B cells and a subset of memory T cells to lymphoid tissue. It also promotes B1 cell migration into the omentum and peritoneum. In the fetus, CXCL13 attracts CD4+ CD3- IL-7 R alpha+ hematopoietic cells to sites of future Peyer's patch development.