E-MSEL-H0028
Mini Sample Human IL-3 (Interleukin-3) ELISA Kit
Größe
£128.70
War £143.00
- SKU:
- E-MSEL-H0028
- Zusätzliche Namen:
- IL3,MCGF,MCSF,MULTI-CSF,P-Cell Stimulating Factor
- Anwendung:
- ELISA
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P08700
- Synonyme:
- colony-stimulating factor, multiple;hematopoietic growth factor;IL-3;interleukin-3;Mast cell growth factor;mast-cell growth factor;MCGF;MULTI-CSF;multilineage-colony-stimulating factor;multipotential colony-stimulating factor;P-cell stimulating factor;P-cell-stimulating factor
- Weitere Details:
- Interleukin-3 (lL-3) is a hemopoietic growth factor involved in the survival,proliferation,and differentiation of multipotent hemopoietic cells. In addition to granulocyte-macrophage colony-stimulating factor (GMCSF) and IL-5,IL-3 is the most potent growth factor for basophils. On mature basophils,these three cytokines act through specific receptors mediating adhesion,migration,and releasability. Mast cells expresses high amounts of IL-3. In the absence of antigen,rapid release of large amount of IL-3 in an autocrine dependent manner is responsible for mast cell survival. IL-3 plays a vital role in stimulating basophils and mast cell responses to parasite infections. IL-3 has also been implicated in the pathogenesis of several chronic inflammatory diseases,including asthma,atherosclerosis,and neurodegenerative disorders,such as multiple sclerosis. IL-3 stimulates colony formation of megakaryocytes,neutrophils,and macrophages from bone marrow cultures. IL-3 is expressed in the major embryonic vessels and regulates the survival and proliferation of hematopoietic stem cells in the early stages of embryonic development.
- Versandbedingungen:
- Blue Ice