Mini Sample Human NGAL ( Neutrophil Gelatinase Associated Lipocalin ) ELISA Kit

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£128.70

War £143.00

SKU:: E-MSEL-H0007
Zusätzliche Namen:: Lipocalin 2,LCN2,Siderocalin
Anwendung:: ELISA
Physischer Zustand:: Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:: Human
Lagerbedingungen:: 2-8[o]C
Hersteller:: Elabscience
Format:: Colorimetric method,ELISA,Sandwich
Uniprot:: P80188
Synonyme:: 24p3;25 kDa alpha-2-microglobulin-related subunit of MMP-9;Lipocalin-2;migration-stimulating factor inhibitor;MSFI;neutrophil gelatinase-associated lipocalin;NGAL;oncogene 24p3;p25;siderocalin LCN2
Weitere Details:: NGAL, also known as lipocalin 2, LCN2, and siderocalin, is a small molecule composed of 178 amino acids. It belongs to the lipocalin superfamily of 20 structurally related secreted proteins. NGAL occurs predominantly in a monomeric form, with a small percentage occurring as a dimer or trimer. It was originally identified as a 25 kD protein covalently bound to gelatinase from human neutrophils. It is a critical component of innate immunity because its ability to bind iron-siderophore complexes limits bacterial growth. Human NGAL is expressed at very low levels in human tissues, including kidney, trachea, lungs, stomach, and colon, and its expression increases greatly in the presence of inflammation and injured epithelia. In addition to its role in innate immunity, it is a promising biomarker for acute kidney injury that is beginning to be used in clinical practice in addition to research studies.