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E-KAB-0680

Human TSP-4 Antibody Pair Set

Größe

£793.80

War £882.00

SKU:
E-KAB-0680
Zusätzliche Namen:
THBS4,thrombospondin 4,Thrombospondin4,Thrombospondin-4,TSP4,TSP-4
Anwendung:
ELISA
Physischer Zustand:
Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:
Human
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Reaktivitäten:
Human
Buffer:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:
TSP-4
Formulierung:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:
P35443
Synonyme:
thrombospondin-4;TSP-4;TSP4
Weitere Details:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation,migration,adhesion and attachment,inflammatory response to CNS injury,regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage,contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response,via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.
Versandbedingungen:
Blue Ice