E-KAB-0676
Human AR Antibody Pair Set
Größe
£793.80
War £882.00
- SKU:
- E-KAB-0676
- Zusätzliche Namen:
- AREG,CRDGF,SDGF
- Anwendung:
- ELISA
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Reaktivitäten:
- Human
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- AR
- Formulierung:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- P15514
- Synonyme:
- amphiregulin;amphiregulin B;AR;AREGB;colorectum cell-derived growth factor;CRDGF;schwannoma-derived growth factor;SDGF
- Weitere Details:
- Amphiregulin was initially identified in the conditioned medium of human mammary gland MCF-7 cells treated with TPA. The mouse gene was cloned from the androgen-dependent SC2G cell line derived from Shionogi mouse mammary carcinoma SC115. It belongs to the EGF family of proteins that includes EGF,TGF-A Alpha,heparin-binding EGF like-growth factor (HB-EGF),epigen,epiregulin,and betacellulin. Mouse amphiregulin is derived from a 248 amino acid transmembrane precursor and it has 66% identity to the human protein. All the EGF family members are synthesized as type I membrane protein precursors,which can undergo proteolytic cleavage at the plasma membrane to release a mature soluble ectodomain. ADAM17 (TACE) has an important role in ectodomain shedding of amphiregulin,TNF-A Alpha,and HB-EGF.
- Versandbedingungen:
- Blue Ice