E-KAB-0594
Mouse BAFF/CD257 Antibody Pair Set
Größe
£793.80
War £882.00
- SKU:
- E-KAB-0594
- Zusätzliche Namen:
- TNFSF13B,BLYS,TALL1,THANK,TNFSF20,ZTNF4
- Anwendung:
- ELISA
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Spezies-Reaktivität:
- Mouse
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Reaktivitäten:
- Mouse
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- BAFF/CD257
- Formulierung:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- Q9WU72
- Synonyme:
- b cell-activating factor;B-cell-activating factor;BAF;BAFF;BL;BLyS;D8Ertd387;D8Ertd387e;TAL;TALL-1;TALL1;THANK;TNFSF20;Tnlg7a;tumor necrosis factor ligand 7a;tumor necrosis factor ligand superfamily member 13B;zTNF;zTNF4
- Weitere Details:
- B cell-activating factor ( BAFF ) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus ( SLE ) . Also , some SLE patients have increased levels of BAFF in serum. Therefore , it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
- Versandbedingungen:
- Blue Ice