E-KAB-0574
Mouse DPP4 Antibody Pair Set
Größe
£460.80
War £512.00
- SKU:
- E-KAB-0574
- Zusätzliche Namen:
- ADABP,ADCP2,Adenosine Deaminase Complexing Protein 2,CD26,DPPIV,TP103
- Anwendung:
- ELISA
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Spezies-Reaktivität:
- Mouse
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Reaktivitäten:
- Mouse
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- DPP4
- Formulierung:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P28843
- Synonyme:
- Cd26;dipeptidyl peptidase 4;dipeptidyl peptidase IV;Dpp;DPP IV;Dpp-4;T-cell activation antigen CD26;THA;THAM;thymocyte-activating molecule
- Weitere Details:
- Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor ( TCR ) -mediated T-cell activation. Acts as a positive regulator of T-cell coactivation , by binding at least ADA , CAV1 , IGF2R , and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix ( ECM ) , the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion , migration and tube formation. When overexpressed , enhanced cell proliferation , a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation , including many chemokines , mitogenic growth factors , neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
- Versandbedingungen:
- Blue Ice