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E-KAB-0560

Mouse ACE Antibody Pair Set

Größe

£793.80

War £882.00

SKU:
E-KAB-0560
Zusätzliche Namen:
ACE1,CD143,DCP,DCP1,ICH,MVCD3
Anwendung:
ELISA
Physischer Zustand:
Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:
Mouse
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Reaktivitäten:
Mouse
Buffer:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:
ACE
Formulierung:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Uniprot:
P09470
Synonyme:
angiotensin-converting enzyme;AW208573;CD143;dipeptidyl carboxypeptidase I;dipeptidyl peptidase;kininase II
Weitere Details:
Dipeptidyl carboxypeptidase that removes dipeptides from the C-terminus of a variety of circulating hormones , such as angiotensin I , bradykinin or enkephalins , thereby playing a key role in the regulation of blood pressure , electrolyte homeostasis or synaptic plasticity.Composed of two similar catalytic domains , each possessing a functional active site , with different selectivity for substrates.Plays a major role in the angiotensin-renin system that regulates blood pressure and sodium retention by the kidney by converting angiotensin I to angiotensin II , resulting in an increase of the vasoconstrictor activity of angiotensin.Also able to inactivate bradykinin , a potent vasodilator , and therefore enhance the blood pressure response.Acts as a regulator of synaptic transmission by mediating cleavage of neuropeptide hormones , such as substance P , neurotensin or enkephalins.Catalyzes degradation of different enkephalin neuropeptides ( Met-enkephalin , Leu-enkephalin , Met-enkephalin-Arg-Phe and possibly Met-enkephalin-Arg-Gly-Leu ) .Acts as a regulator of synaptic plasticity in the nucleus accumbens of the brain by mediating cleavage of Met-enkephalin-Arg-Phe , a strong ligand of Mu-type opioid receptor OPRM1 , into Met-enkephalin.
Versandbedingungen:
Blue Ice