Human CD276 Antibody Pair Set

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£460.80

War £512.00

SKU:: E-KAB-0414
Zusätzliche Namen:: 4Ig-B7-H3,B7-H3,B7H3,B7RP-2
Anwendung:: ELISA
Physischer Zustand:: Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:: Human
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Reaktivitäten:: Human
Buffer:: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:: CD276
Formulierung:: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Uniprot:: Q5ZPR3-1
Synonyme:: 4Ig-B7-H3;B7 homolog 3;Costimulatory molecule
Weitere Details:: The protein encoded by this gene belongs to the immunoglobulin superfamily , and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors , the protein is preferentially expressed only in tumor tissues. Additionally , it was observed that the 3&apos , UTR of this transcript contains a target site for miR29 microRNA , and there is an inverse correlation between the expression of this protein and miR29 levels , suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.