E-KAB-0405
Human sgp130 Antibody Pair Set
Größe
£793.80
War £882.00
- SKU:
- E-KAB-0405
- Zusätzliche Namen:
- CD130,CDW130,IL-6RB,IL6ST,IR6RB,Interleukin 6 signal transducer
- Anwendung:
- ELISA
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Reaktivitäten:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- sgp130
- Formulierung:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P40189
- Synonyme:
- CD130;CD130 antigen;CDW130;GP130;gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form;gp130, oncostatin M receptor;HIES4;IL-6 receptor subunit beta;IL-6R subunit beta;IL-6RB;interleukin receptor beta chain;interleukin-6 receptor subunit beta;interleukin-6 signal transducer;membrane glycoprotein 130;membrane glycoprotein gp130;oncostatin-M receptor subunit alpha;sGP130
- Weitere Details:
- The protein encoded by this gene is a signal transducer shared by many cytokines , including interleukin 6 ( IL6 ) , ciliary neurotrophic factor ( CNTF ) , leukemia inhibitory factor ( LIF ) , and oncostatin M ( OSM ) . This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6 , a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus , can bypass the interleukin 6 receptor ( IL6R ) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
- Versandbedingungen:
- Blue Ice