E-KAB-0345
Mouse IL-6R Antibody Pair Set
Größe
£793.80
War £882.00
- SKU:
- E-KAB-0345
- Zusätzliche Namen:
- Il6r,Il6ra
- Anwendung:
- ELISA
- Spezies-Reaktivität:
- Mouse
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Reaktivitäten:
- Mouse
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- IL-6R
- Formulierung:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- P22272
- Synonyme:
- CD126;I;IL;IL-6 receptor alpha chain;IL-6 receptor subunit alpha;IL-6R;IL-6R 1;IL-6R subunit alpha;IL-6R-alpha;IL-6RA;Il6r;interleukin-6 receptor subunit alpha
- Weitere Details:
- Part of the receptor for interleukin 6. Binds to IL6 with low affinity,but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response,acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling',the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively,'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
- Versandbedingungen:
- Blue Ice