Human LGALS3BP Antibody Pair Set

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£793.80

War £882.00

SKU:: E-KAB-0265
Zusätzliche Namen:: LGALS3BP,90K,BTBD17B,CyCAP,M2BP,MAC-2-BP,TANGO10B,gp90
Anwendung:: ELISA
Spezies-Reaktivität:: Human
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Reaktivitäten:: Human
Buffer:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:: LGALS3BP
Formulierung:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:: Q08380
Synonyme:: 90K;basement membrane autoantigen p105;BTBD17B;CyCAP;galectin-3-binding protein;gp90;L3 antigen;lectin galactoside-binding soluble 3-binding protein;M2BP;mac-2 BP;Mac-2-binding protein;MAC-2-BP;MAC2BP;serum protein 90K;TANGO10B;transport and golgi organization 10 homolog B;tumor-associated antigen 90K
Weitere Details:: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP is a widely expressed,secreted galectin. It has been found elevated in the serum of patients with various types of breast,lung,colorectal,ovary,and endometrial cancer,and in those infected by the human immunodeficiency virus (HIV). High expression levels of LGALS3BP are associated with a shorter survival,the occurrence of metastasis or a reduced response to chemotherapy. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Immunoblotting showed that LGALS3BP is likely contained in breast milk,serum,semen,saliva,urine,and tears.

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