E-EL-M3131
Mouse IL-17C (Interleukin 17C) ELISA Kit
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£120.60
War £134.00
- SKU:
- E-EL-M3131
- Zusätzliche Namen:
- Interleukin-17C,Il-17c,Cytokine CX2
- Anwendung:
- ELISA
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Spezies-Reaktivität:
- Mouse
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Elabscience
- Reaktivitäten:
- Mouse
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- Q8K4C5
- Synonyme:
- cytokine CX2;IL-1;IL-17C;interleukin-17C
- Weitere Details:
- IL-17C(Interleukin 17C) is a pro-inflammatory cytokine that plays a crucial role in epithelial innate immunity, especially against intestinal bacterial pathogens, acting in an autocrine manner. It stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense via activating the NFKB and MAPK signaling pathways. It acts synergistically with IL22, TNF and IL1B to induce antibacterial peptides. It may exert a protective effect by maintaining epithelial homeostasis after inflammatory challenges, such as intestinal inflammation in a dextran sulfate sodium-induced colitis model. It can also promote an inflammatory phenotype, e.g., in psoriatic skin. Enhanced IL17C/IL17RE signaling may increase susceptibility to autoimmune diseases like autoimmune encephalitis.
- Versandbedingungen:
- Blue Ice