Mouse FcE EpsilonRII/CD23(Receptor II for the Fc Region of Immunoglobulin E) ELISA Kit

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£128.70

War £143.00

SKU:: E-EL-M2432
Zusätzliche Namen:: FCER2,BLAST-2,CD23A,CLEC4J,FCE2,IGEBF,Fc epsilon RII,FcE EpsilonRII
Anwendung:: ELISA
Physischer Zustand:: Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:: Mouse
Lagerbedingungen:: 2-8[o]C
Hersteller:: Elabscience
Format:: Colorimetric method,ELISA,Sandwich
Uniprot:: P20693
Synonyme:: CD23;FC epsilon RII;fc-epsilon-RII;Fce2;Fcer2;low affinity immunoglobulin epsilon Fc receptor;low-affinity IgE receptor;Ly-4;Ly-42;lymphocyte IgE receptor
Weitere Details:: CD23 is a 45 kD protein, also known as Leu-20, FcE EpsilonRII, IgE Fc receptor, BLAST-2, B6, and low affinity IgE receptor. CD23 responds to high levels of IgE by downregulating IgE secretion. In human monocytes, CD23 triggering results in release of pro-inflammatory cytokines including TNF-A Alpha, IL-1, IL-6, and GM-CSF. CD23 can be proteolytically cleaved to generate soluble CD23 fragments of various molecular weights. In chronic lymphocytic leukemia, levels of soluble CD23 in the serum can be used as a prognostic marker to identify patients at high risk for disease progression.