E-EL-H6278
Human CFD (Complement Factor D) ELISA Kit
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£128.70
War £143.00
- SKU:
- E-EL-H6278
- Zusätzliche Namen:
- ADN,Adipsin,DF,PFD,Factor D,Properdin Factor D Esterase
- Anwendung:
- ELISA
- Physischer Zustand:
- Other Biological Fluid, Plasma, Serum
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P00746
- Synonyme:
- ADIPSIN;ADN;C3 convertase activator;complement factor D;complement factor D preproprotein;D component of complement (adipsin);DF;PFD;properdin factor D
- Weitere Details:
- This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
- Versandbedingungen:
- Blue Ice