LTB4(Leukotriene B4) ELISA Kit

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£128.70

War £143.00

SKU:: E-EL-0061
Zusätzliche Namen:: Leukotriene B4
Anwendung:: ELISA
Physischer Zustand:: Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:: Wide/Non-species Specific
Lagerbedingungen:: 2-8[o]C
Hersteller:: Elabscience
Format:: Colorimetric method,ELISA,Competitive
Weitere Details:: Leukotriene B4 [LTB4, (5S,12R)-5,12-dihydroxy-(Z,E,E,Z)-6,8,10,14-eicosatetraenoic acid] is a potent chemotactic agentgenerated enzymatically in leukocytes from arachidonic acid viathe 5-lipoxygenase pathway. Previous studies demonstrated thatLTB4 is generated in several cell types including polymorphonuclear leukocytes (PMNs), macrophages, and monocytes . Asa potent chemotactic agent, LTB4 is regarded as an importantmediator in several pathological processes such as inflammatoryand allergic responses. To understand the role of LTB4 in thesepathological processes, an accurate and reliable analytical methodto determine the concentration of LTB4 in biological fluids isrequired. However, due to the very low concentration of endogenous LTB4 and the potential interference from other endogenouscompounds in the biological fluids, it is challenging to develop asufficiently sensitive and selective method.