PGI2(Prostacyclin) ELISA Kit

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£128.70

War £143.00

SKU:: E-EL-0022
Zusätzliche Namen:: PGI2,prostaglandin I2
Anwendung:: ELISA
Physischer Zustand:: Other Biological Fluid, Plasma, Serum
Spezies-Reaktivität:: Wide/Non-species Specific
Lagerbedingungen:: 2-8[o]C
Hersteller:: Elabscience
Format:: Colorimetric method,ELISA,Competitive
Weitere Details:: Prostacyclin (PGI2) is involved in platelet aggregation, vasoconstriction, and reproductive functions. PGI2 has a half life of 60 minutes in plasma but only 2 to 3 minutes in buffer. The production of PGI2 is typically monitored by measurement of 6k-PGF1A Alpha and 2,3d-6k- PGF1A Alpha. 6-keto- PGF1A Alpha is produced by the non-enzymatic hydration of PGI2, and is further metabolized in urine to the 2,3-dinor derivative. A number of pharmaceuticals alter andor inhibit the synthesis of PGI2. Methods to measure PGI2 in urine typically involve HPLC, gas chromatographymass spectrometry, or radioimmunoassay and enzyme immunoassay for 6k- PGF1A Alpha.