E-AB-F1418D
PE Anti-Human CD195 Antibody[RoAb13]
Größe
£115.20
War £128.00
- SKU:
- E-AB-F1418D
- Anwendung:
- Flow Cytometry
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- CD195
- Klon:
- RoAb13
- Uniprot:
- P51681
- Synonyme:
- C-C chemokine receptor type 5;C-C motif chemokine receptor 5 A159A;CC-CKR-5;CCCKR5;CCR-5;CD195;chemokine (C-C motif) receptor 5;chemokine receptor CCR5;chemokine recptor CCR5 Delta32;chemr13;CKR-5;CKR5;CMKBR5;HIV-1 fusion coreceptor;IDDM22;mutant C-C motif chemokine receptor
- Weitere Details:
- CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1A Alpha, MIP-1B Beta, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry, modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
- Versandbedingungen:
- Blue Ice