E-AB-F12720
Purified Anti-Mouse IL-17A Antibody[17F3], Functional Grade
Größe
£80.10
War £89.00
- SKU:
- E-AB-F12720
- Zusätzliche Namen:
- IL-17CTLA,Cytotoxic T-lymphocyte-associated antigen,IL-17Acytotoxic T-lymphocyte-associated protein,CTLA8cytotoxic T-lymphocyte-associated serine esterase,CTLA 8,CTLA8cytotoxic T-lymphocyte-associated serine esterase 8,Ctla9,IL-17A,IL-17Acytotoxic T-lymphocyte-associated protein 8,IL-17CTLA-8,Interleukin-17A,IL-17,CTLA-8,Il17a,Cytotoxic T-lymphocyte-associated antigen 8,Ctla8,Il17,CTLA8,CTLA-8,CTLA8cytotoxic T-lymphocyte-associated serine esterase 8,Cytotoxic T-lymphocyte-associated antigen
- Anwendung:
- Flow Cytometry
- Konzentration:
- >= 1 mg/ml
- Aufreinigung:
- protein a/g purified
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Mouse IL-17A protein
- Klon:
- 17F3
- Uniprot:
- Q62386
- Synonyme:
- Ctl;Ctla;Ctla-8;Ctla8;cytotoxic T-lymphocyte-associated antigen 8;Il;IL-;IL-17;IL-17A;Il17;interleukin-17A
- Weitere Details:
- The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, G GammaD Delta T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A in vivo. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Versandbedingungen:
- Blue Ice