APC Anti-Human/Monkey CD16 Antibody[3G8]

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£108.00

War £120.00

SKU:: E-AB-F1236E
Zusätzliche Namen:: Fc gamma receptor,Fc gamma receptor 3,FcG GammaRIII
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: CD16
Klon:: 3G8
Uniprot:: O75015, P08637
Synonyme:: activation B7-1 antigen;B-lymphocyte activation antigen B7;B7;B7-1;B7.1;BB1;CD16;CD16A;CD16a antigen;CD16b;CD28LG;CD28LG1;CD80 antigen (CD28 antigen ligand 1, B7-1 antigen);costimulatory factor CD80;costimulatory molecule variant IgV-CD80;CTLA-4 counter-receptor B7.1;Fc fragment of IgG, low affinity III, receptor for (CD16);Fc fragment of IgG, low affinity IIIa, receptor (CD16a);Fc fragment of IgG, low affinity IIIb, receptor (CD16b);Fc gamma receptor III-A;Fc gamma receptor III-B;Fc gamma receptor IIIb;Fc-gamma receptor III-2 (CD 16);Fc-gamma receptor IIIb (CD 16);Fc-gamma receptor IIIb (CD16);Fc-gamma RIII-alpha;fc-gamma RIII-beta;fc-gamma RIIIb;FCG3;FcgammaRIIIA;FCGR3;FCGR3A;FCGRIII;FCR-10;FCRIII;FCRIIIA;FCRIIIb;IGFR3;igG Fc receptor III-1;igG Fc receptor III-2;IMD20;immunoglobulin G Fc receptor III;LAB7;low affinity immunoglobulin gamma Fc region receptor III-A;low affinity immunoglobulin gamma Fc region receptor III-B;low affinity immunoglobulin gamma receptor III-a Fc fragment;neutrophil-specific antigen NA;T-lymphocyte activation antigen CD80
Weitere Details:: CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Versandbedingungen:: Blue Ice