E-AB-F12360
Purified Anti-Human/Monkey CD16 Antibody[3G8], Functional Grade
Größe
£80.10
War £89.00
- SKU:
- E-AB-F12360
- Zusätzliche Namen:
- FCR,IMD,FCG,Fcgr,IGFR,IgG Fc Receptor III,CD16,CD16A,FCG3,FCGR3,FCGRIII,FCR-10,FCRIII,FCRIIIA,IGFR3,IMD20,FCGR3A,CD16a Antigen,Fc-Gamma RIII,Fc-gamma RIIIa,Fc-Gamma RIII-Alpha,IgG Fc Receptor III-2,Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A,Fc&,gamma-RIIIA-A, CD16a,CD 16,CD 16a,CD16B,CD16b antigen,Fc fragment of IgG,Fc fragment of IgG low affinity IIIa receptor,Fc fragment of IgG low affinity IIIa receptor (CD16),Fc fragment of IgG receptor IIIa,Fc gamma R3,Fc gamma receptor
- Anwendung:
- Flow Cytometry, Neutralisation
- Konzentration:
- >= 1 mg/ml
- Aufreinigung:
- protein a/g purified
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Human CD16 protein
- Klon:
- 3G8
- Uniprot:
- O75015, P08637
- Synonyme:
- CD16;CD16A;CD16a antigen;CD16b;Fc fragment of IgG, low affinity III, receptor for (CD16);Fc fragment of IgG, low affinity IIIa, receptor (CD16a);Fc fragment of IgG, low affinity IIIb, receptor (CD16b);Fc gamma receptor III-A;Fc gamma receptor III-B;Fc gamma receptor IIIb;Fc-gamma receptor III-2 (CD 16);Fc-gamma receptor IIIb (CD 16);Fc-gamma receptor IIIb (CD16);Fc-gamma RIII-alpha;fc-gamma RIII-beta;fc-gamma RIIIb;FCG3;FcgammaRIIIA;FCGR3;FCGR3A;FCGRIII;FCR-10;FCRIII;FCRIIIA;FCRIIIb;IGFR3;igG Fc receptor III-1;igG Fc receptor III-2;IMD20;immunoglobulin G Fc receptor III;low affinity immunoglobulin gamma Fc region receptor III-A;low affinity immunoglobulin gamma Fc region receptor III-B;low affinity immunoglobulin gamma receptor III-a Fc fragment;neutrophil-specific antigen NA
- Weitere Details:
- CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Versandbedingungen:
- Blue Ice