APC Anti-Human/Monkey CD20 Antibody[2H7]

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£95.40

War £106.00

SKU:: E-AB-F1212E
Zusätzliche Namen:: B-lymphocyte surface antigen B1,Bp35,Leukocyte surface antigen Leu-16,MS4A1
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: CD20
Klon:: 2H7
Uniprot:: P11836
Synonyme:: B-lymphocyte antigen CD20;B-lymphocyte cell-surface antigen B1;B-lymphocyte surface antigen B1;B1;Bp35;CD20;CD20 antigen;CD20 receptor;CVID5;FMC7;LEU-16;leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;membrane-spanning 4-domains, subfamily A, member 1;S7
Weitere Details:: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.