E-AB-F12120
Purified Anti-Human/Monkey CD20 Antibody[2H7], Functional Grade
Größe
£80.10
War £89.00
- SKU:
- E-AB-F12120
- Zusätzliche Namen:
- B-lymphocyte surface antigen B1,Bp35,Leukocyte surface antigen Leu-16,MS4A1
- Anwendung:
- Flow Cytometry
- Konzentration:
- >= 1 mg/ml
- Aufreinigung:
- protein a/g purified
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Human CD20 protein
- Klon:
- 2H7
- Uniprot:
- P11836
- Synonyme:
- B-lymphocyte antigen CD20;B-lymphocyte cell-surface antigen B1;B-lymphocyte surface antigen B1;B1;Bp35;CD20;CD20 antigen;CD20 receptor;CVID5;FMC7;LEU-16;leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;membrane-spanning 4-domains, subfamily A, member 1;S7
- Weitere Details:
- CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Versandbedingungen:
- Blue Ice